Greg was first elected as the MLA for Yorkton in the 2007 provincial election. He was re-elected in 2011, 2016 and 2020. Born in Regina, Greg is a long-time resident of Yorkton and a man who has always been involved in his community. Prior to being elected, Greg owned and operated Ottenbreit Waste Systems, a private environmental and waste disposal business. He is an avid motorsports enthusiast and commercial pilot.

Greg has been married to his high school sweetheart, Leone, since 1986. They have two daughters, Katelin, son-in-law Mark and two grandchildren, Raya and Malaya, and Rayanne, son-in-law, Austin, a granddaughter, Wynnslet and grandsons Otto and Crew.

In 1998, Greg and Leone started "Brayden Ottenbreit Close Cuts for Cancer" – an event that encourages volunteers to shave their heads to raise money for cancer research and local initiatives. The charity is named in honour of their son, Brayden, who lost his battle with cancer in 2000 at age 5. Approximately $1 million has been raised for cancer research and local cancer initiatives. In recognition of these efforts, they received the Community Merit Award in 2016, presented by the Yorkton Chamber of Commerce, as well as, national recognition from the Canadian Cancer Society and other philanthropic organizations.

Because of their community involvement and volunteerism, Greg and Leone were recognized in 2005 with the Saskatchewan Centennial Medal. Greg was recognized again in 2012 with the Hal Rogers Fellow Award, the highest honour presented by the Kinsmen of Canada. Leone and Greg have also been awarded the Queen’s Diamond Jubilee award.

On August 13, 2019, Greg was appointed Minister of Highways and Infrastructure, and Minister Responsible for the Water Security Agency, and Saskatchewan Ukraine relations. He served in this capacity until the 2020 General Election. He previously served as Minister Responsible for Rural and Remote Health from September 2014 to August 2019. Greg was appointed Government Whip on November 9th, 2020.

Prior to his time in Cabinet, Greg worked as a Legislative Secretary to the Minister of Social Services (Community-Based Organizations initiative), a Legislative Secretary to the Minister of Environment (Recycling), and as a Legislative Secretary to the Premier (Vulnerable Youth). Greg has also served as Deputy Government Whip, Government Whip, and as the Chair of the Standing Committee on Human Services.